Methylated B Complex (BioCare, 60 Capsules)

£20.00

BioCare Methyl B Complex provides a full range of B vitamins in their methylated, ready-to-use forms: folate as calcium L-methylfolate, B12 as methylcobalamin and adenosylcobalamin, and B6 as pyridoxal-5-phosphate (P-5-P). These forms skip a conversion step that the body would otherwise need to perform to activate standard folic acid and cyanocobalamin.

Vitamin B12 and folate contribute to normal blood formation, normal homocysteine metabolism, normal psychological function, and the reduction of tiredness and fatigue. Vitamin B6 contributes to the regulation of hormonal activity, normal psychological function, and normal red blood cell formation.

This is a food supplement and should not be used as a substitute for a varied and balanced diet or a healthy lifestyle. It is not intended to diagnose, treat, cure, or prevent any disease.

Important: please read the safety note on Vitamin B6 dosage below before taking this product long-term.

- Vitamin B12 and folate contribute to normal blood formation and normal homocysteine metabolism
- Vitamin B12, folate, and B6 contribute to normal psychological function
- Contributes to the reduction of tiredness and fatigue
- Vitamin B6 contributes to the regulation of hormonal activity
- Provided in methylated, ready-to-use forms (methylfolate, methylcobalamin, P-5-P)
- Vegan and vegetarian formulation

Biocare Methyl B Complex provides B vitamins in their most bioavailable, metabolically active forms. Unlike standard B complexes that require liver conversion, this methylated b complex delivers folate as methylfolate, B12 as methylcobalamin, and B6 as P-5-P – ready for immediate use.

Methylated b vitamins are particularly beneficial for individuals with MTHFR gene variations who struggle to convert standard folic acid. The methylated b complex is better absorbed and more effective for everyone. BioCare is a trusted UK brand with over 35 years of expertise in practitioner-grade nutritional supplements.

Each capsule contains Vitamin B1 (Thiamine Hydrochloride) 25mg, Vitamin B2 (Riboflavin-5-Phosphate) 25mg, Niacin (Vitamin B3) 25mg, Vitamin B6 (Pyridoxal-5-Phosphate) 25mg, Folate as Calcium L-methylfolate 250µg, Vitamin B12 (Adenosylcobalamin & Methylcobalamin) 250µg, Biotin 200µg, and Pantothenic Acid (Vitamin B5) 25mg. It also includes Choline, Inositol, and PABA at 25mg each. Other ingredients include Capsule Shell (HPMC), Silicon Dioxide, and Magnesium Stearate.

Daily values not established for all ingredients. % EC NRV for certain nutrients: Vitamin B12 10000%, Folate 125%, Biotin 400%, Vitamin B6 1786%.

Take 1 capsule daily with food, or as professionally directed.

Do not exceed the stated recommended daily intake.
Long-term intake of amounts greater than 10mg of vitamin B6 daily may lead to mild tingling and numbness.
If you are under medical supervision, pregnant, nursing, or taking medication, consult a doctor before use.
Do not use if seal is broken.
Keep out of reach of children.
This product should not be used as a substitute for a varied diet and healthy lifestyle.

This information is not a substitute for professional medical advice. Always seek the advice of your physician.

At Insight Integrative Health Clinic, we recommend blood testing and clinical guidance before starting supplementation, especially for those with MTHFR variations or unexplained fatigue.

Frequently asked questions

Everything you need to know before you order.

What does "methylated" actually mean, and why does it matter?

Standard B vitamin supplements often use forms like folic acid and cyanocobalamin, which the body needs to convert into their active forms before it can use them. This product provides folate, B12, and B6 already in their active, ready-to-use forms, skipping that conversion step.

I've heard methylated B vitamins are better for people with MTHFR gene variations. Is that right?

Yes, this is the strongest, most specific rationale for methylated B vitamins. Some people have a genetic variation in the MTHFR enzyme that makes it harder to convert standard folic acid into its active form, so methylfolate can be a particularly relevant choice for them. We'd be cautious about extending this into a claim that methylated forms are better for everyone, since that's a different, less well-supported claim.

How do I take it?

1 capsule daily, or as directed by your healthcare practitioner. Please don't exceed the stated recommended daily intake.

Is it safe to take this every day, long-term?

This is worth reading carefully. This product provides 25mg of Vitamin B6 per capsule. Long-term intake of more than 10mg of Vitamin B6 daily has been associated with tingling and numbness (peripheral neuropathy) in some people. At the standard 1-capsule daily dose, this product already exceeds that 10mg threshold, so we'd recommend discussing long-term daily use with your practitioner, particularly if you're also taking B6 from other supplements or fortified foods.

Is this suitable for vegans?

Yes, it's vegan and vegetarian.

Does this treat depression, anxiety, or any other diagnosed condition?

No. This is a food supplement, not a medicine. B vitamins contribute to normal psychological function and the reduction of tiredness and fatigue, which are authorised claims, but this product is not intended to diagnose, treat, cure, or prevent any medical or mental health condition.

Should I get tested for MTHFR before taking this?

That's a conversation worth having with your practitioner. We're not aware of strong evidence that routine MTHFR testing changes outcomes for most people, but your practitioner can advise whether it's relevant to your specific situation.

A More Thoughtful Approach to Health

For over 40 years, Insight Care Clinic has helped patients across London take a more personalised and integrative approach to long-term wellbeing. Our consultations look beyond symptoms to understand the full picture of your health, combining practitioner expertise, integrative therapies, and tailored guidance to support lasting balance and wellbeing.

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